Individualized Treatment in Distal and Medium Vessel Occlusion Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model
Although aggregate outcomes did not differ significantly, the validated Distal and Medium Vessel Occlusion Stroke (DUSK) Tool enables individualized estimation of EVT benefit in DMVO stroke. This explainable counterfactual treatment estimation framework supports precision decision making by identifying specific patient subgroups most likely to benefit from EVT over MM. ANN NEUROL 2026.
Authors
- Mahmoud H. Mohammaden (ORCID: https://orcid.org/0000-0002-7393-9989)
- Manuel Requena
- James Ernest Siegler (ORCID: https://orcid.org/0000-0003-0287-3967)
- Marc Rodrigo‐Gisbert (ORCID: https://orcid.org/0000-0002-7953-3795)
- Johanna T. Fifi
- Santiago Ortega‐Gutierrez
- Wei Hu
- Ali Alaraj
- Diogo C. Haussen
- Mohamad Abdalkader
- Thanh N. Nguyen
- Raul G. Nogueira
- Mohamed F. Doheim
- Hend Abdelhamid
- Marta Olive‐Gadea
Institutions
- Boston University (US)
- University of Science and Technology of China (CN)
- Grady Memorial Hospital (US)
- Emory University (US)
- University of Iowa Hospitals and Clinics (US)
- University of Illinois Chicago (US)
- University of Chicago (US)
- Vall d'Hebron Hospital Universitari (ES)
- University of Pittsburgh Medical Center (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Annals of Neurology
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1002/ana.78168
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00