Co(III)-Catalyzed C5–H Amination of Thiochromones with Anthranils
The incorporation of a nitrogen unit into target molecules by generating nitrene species has become a hot topic in modern organic synthesis. In this study, we report a Co(III)-catalyzed C5-H amination of thiochromones with anthranils as aminating surrogates. The significance of this coupling reaction was demonstrated via a broad range of substrates and complete site selectivity. Moreover, post-transformations of synthesized products are described.
Authors
- Jeonghyun Min
- Amitava Rakshit (ORCID: https://orcid.org/0000-0002-2605-9401)
- Keunju Park
- In Su Kim
- Youngchang Kim (ORCID: https://orcid.org/0000-0002-1610-4889)
- Anand Kumar (ORCID: https://orcid.org/0009-0002-8058-8491)
- Pargat Singh (ORCID: https://orcid.org/0000-0002-0203-0612)
- Joon-Ho Lee
- Seungyeon Lee
Institutions
- Korea Research Institute of Chemical Technology (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1021/acs.joc.5c03162
- Primary Topic
- Synthesis and Catalytic Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00