Efficacy and safety of Ixazomib-based maintenance therapy after autologous hematopoietic stem cell transplantation in multiple myeloma patients: a retrospective analysis

Within the constraints of the current Chinese clinical context, ixazomib-based maintenance therapy demonstrates favorable efficacy and a manageable safety profile for MM patients after ASCT, offering a viable and accessible alternative. Achieving sustained MRD negativity is critically important for long-term outcomes, reinforcing its value as a key treatment goal. These real-world findings support the role of ixazomib, particularly for patients ineligible for or intolerant to standard regimens.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-29
DOI
https://doi.org/10.3389/fmed.2026.1680704
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Efficacy and safety of Ixazomib-based maintenance therapy after autologous hematopoietic stem cell transplantation in multiple myeloma patients: a retrospective analysis

Kaile Zhang, Chunxia Han, Hailong Yuan, Jianli Xu et al.
Frontiers in Medicine
Multiple Myeloma Research and Treatments
article

Efficacy and safety of Ixazomib-based maintenance therapy after autologous hematopoietic stem cell transplantation in multiple myeloma patients: a retrospective analysis

Kaile Zhang, Chunxia Han, Hailong Yuan, Jianli Xu, Ming Jiang, Gang Chen, Jia Hou, Mengyuan Chen, Ruixue Yang
article en

Abstract

Within the constraints of the current Chinese clinical context, ixazomib-based maintenance therapy demonstrates favorable efficacy and a manageable safety profile for MM patients after ASCT, offering a viable and accessible alternative. Achieving sustained MRD negativity is critically important for long-term outcomes, reinforcing its value as a key treatment goal. These real-world findings support the role of ixazomib, particularly for patients ineligible for or intolerant to standard regimens.

Frontiers in MedicineVol. 13
Xinjiang Medical University (CN), First Affiliated Hospital of Xinjiang Medical University (CN)
Good health and well-being
Openalex Percentile: Top 77%
Multiple Myeloma Research and Treatments
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Efficacy and safety of Ixazomib-based maintenance therapy after autologous hematopoietic stem cell transplantation in multiple myeloma patients: a retrospective analysis — Kaile Zhang, Chunxia Han, et al. · Frontiers in Medicine (2026) | TGRS Research Map | TGRS