Efficacy and safety of Ixazomib-based maintenance therapy after autologous hematopoietic stem cell transplantation in multiple myeloma patients: a retrospective analysis
Within the constraints of the current Chinese clinical context, ixazomib-based maintenance therapy demonstrates favorable efficacy and a manageable safety profile for MM patients after ASCT, offering a viable and accessible alternative. Achieving sustained MRD negativity is critically important for long-term outcomes, reinforcing its value as a key treatment goal. These real-world findings support the role of ixazomib, particularly for patients ineligible for or intolerant to standard regimens.
Authors
- Kaile Zhang (ORCID: https://orcid.org/0000-0001-6910-8050)
- Chunxia Han (ORCID: https://orcid.org/0009-0009-0261-1810)
- Hailong Yuan (ORCID: https://orcid.org/0000-0002-6251-2285)
- Jianli Xu (ORCID: https://orcid.org/0000-0002-9538-0370)
- Ming Jiang
- Gang Chen
- Jia Hou
- Mengyuan Chen
- Ruixue Yang
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-29
- DOI
- https://doi.org/10.3389/fmed.2026.1680704
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00