The Effect of Pertussis Vaccination During Pregnancy on the Binding Epitopes and Avidity of Anti–Pertussis Toxin Immunoglobulin G Antibodies in Infants and Their Mothers
Immunization during pregnancy decreased primary vaccination-induced antibody responses disproportionately against different PT epitopes in infants.The trial was registered in the EU Clinical Trial database (EudraCT number 2019-001986-34, https://www.clinicaltrialsregister.eu).
Authors
- Lauri Ivaska (ORCID: https://orcid.org/0000-0001-8935-5032)
- Pieter G. M. van Gageldonk (ORCID: https://orcid.org/0000-0003-2753-9674)
- A. Buisman
- Aapo Knuutila (ORCID: https://orcid.org/0000-0003-0622-5043)
- Jussi Mertsola (ORCID: https://orcid.org/0000-0002-7746-3949)
- Qiushui He
- Alex-Mikael Barkoff
Institutions
- University of Turku (FI)
- Turku University of Applied Sciences (FI)
- Turku University Hospital (FI)
- National Institute for Public Health and the Environment (NL)
- Turku Centre for Biotechnology (FI)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1093/infdis/jiag048
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00