Prognostic value of lymphatic vessel density in the capsule of early-stage hepatocellular carcinoma: implications for postoperative recurrence risk
High LVD in the tumor capsule was associated with worse OS, RFS, and intrahepatic spread (MVI and satellite nodules) in patients with HCC at BCLC stages 0-A after liver resection. Our findings suggest that assessing LVD in the tumor capsule could serve as a useful tool in predicting postoperative prognosis and guiding personalized treatment strategies for patients with early-stage HCC.
Authors
- Yu-Bo Liang (ORCID: https://orcid.org/0000-0001-6897-5072)
- Jin-Xiang Zuo (ORCID: https://orcid.org/0009-0001-5704-0041)
- Kui Xiang (ORCID: https://orcid.org/0000-0003-3600-8779)
- Xing-Ming Chen
- Q. Wang
- Yawhan Lakang
- Zisheng Yang
- Jin Li
- Yu-Kai Li
- Wan-Ling Luo
- Xin-Wu Lv
- Zhi-Yan Ou
- Yang Ke
- Hao-Wen Qin
- Yan Wang
Institutions
- Kunming Medical University (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-28
- DOI
- https://doi.org/10.3389/fimmu.2026.1714314
- Primary Topic
- Lymphatic System and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00