Shared genetic architecture between schizophrenia and gastrointestinal diseases: insights from large-scale genome-wide cross-trait analysis
Our findings support a shared genetic architecture between SCZ and gastrointestinal diseases and shed light on the potential mechanism that might involve in.These findings hold important implications for coordinated interventions targeting SCZ and its comorbid conditions.
Authors
- Leichang Zhang (ORCID: https://orcid.org/0009-0005-9503-8267)
- Pan Shen (ORCID: https://orcid.org/0000-0003-3374-0382)
- Yifan Ding
- Chenwei Deng (ORCID: https://orcid.org/0000-0002-3747-5128)
- Jiawen Wang (ORCID: https://orcid.org/0000-0003-2317-1390)
- Qinghua Luo
- Zhiqiang Xu
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Annals of General Psychiatry
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1186/s12991-025-00625-2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Jiangxi Provincial Department of Science and Technology