Shox2 and Rassf1a DNA methylation: diagnostic utility and association with clinical stage, histological progression and gene mutational landscape in lung adenocarcinoma

Our study demonstrated that comprehensive analysis of methylation and gene mutations could provide a novel clinical strategy for molecular subtyping and precision medicine in LUAD.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-28
DOI
https://doi.org/10.3389/fonc.2026.1727695
Primary Topic
Epigenetics and DNA Methylation
Type
article
Field-Weighted Citation Impact
0.00

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article

Shox2 and Rassf1a DNA methylation: diagnostic utility and association with clinical stage, histological progression and gene mutational landscape in lung adenocarcinoma

Linguo Xiang, Yiming Li, Xi Zhang, Yangli Zhang et al.
Frontiers in Oncology
Epigenetics and DNA Methylation
article

Shox2 and Rassf1a DNA methylation: diagnostic utility and association with clinical stage, histological progression and gene mutational landscape in lung adenocarcinoma

Linguo Xiang, Yiming Li, Xi Zhang, Yangli Zhang, Zhangling Liu, Yulu Tan, Abida Alimu, Jia Li
article en

Abstract

Our study demonstrated that comprehensive analysis of methylation and gene mutations could provide a novel clinical strategy for molecular subtyping and precision medicine in LUAD.

Frontiers in OncologyVol. 16
The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Chongqing Medical University
Good health and well-being
Openalex Percentile: Top 75%
Epigenetics and DNA Methylation
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