Estimating the probability of experiencing an improvement in randomized controlled trials based on anchor-based MIC studies – An alternative to responder analyses
Estimating the probability of experiencing an improvement provides an alternative to responder analyses. This approach makes more efficient use of information comprised in the data from anchor-based MIC studies than the translation into MIC values to inform the choice of thresholds in a responder analysis.
Authors
- Franziska Saxer (ORCID: https://orcid.org/0000-0003-4153-6795)
- Werner Vach
Institutions
- Novartis (Switzerland) (CH)
- University of Southern Denmark (DK)
- University of Basel (CH)
Publication Details
- Journal
- Contemporary Clinical Trials
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1016/j.cct.2026.108243
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 0.00