Transcriptional and neurotransmitter signatures associated with regional gray matter alterations in juvenile myoclonic epilepsy
While these associations are based on data from healthy donors and require further validation, our findings bridge the gap between macroscopic brain alterations and their underlying molecular architecture in JME. This provides an integrated model of its pathophysiology and highlights potential therapeutic avenues.
Authors
- Xu Han (ORCID: https://orcid.org/0000-0001-5410-2502)
- Si-Yu Gu
- Chuan-Xu Luo
- Hucheng Yang
- Ping-Lei Pan
- Shu Wang
- Xiao-Yi Liu
- Wen-Hui Li
Institutions
- Yancheng Third People's Hospital (CN)
- Weihai Maternal and Child Health Hospital (CN)
- Yancheng Second People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Molecular Neuroscience
- Published
- 2026-01-29
- DOI
- https://doi.org/10.3389/fnmol.2026.1693722
- Primary Topic
- Glycogen Storage Diseases and Myoclonus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nantong University
- Bijzonder Onderzoeksfonds UGent