Ellagic Acid Alleviates Abnormal Fat Reduction by Activating the RXRβ–PPARγ Pathways in a CT26 Tumour‐Induced Cachexia Mouse Model
EA mitigates cancer cachexia-induced fat loss by the activation of the RXRβ-PPARγ pathway. These findings present EA as a potential pharmacological agent to improve the abnormal fat reduction and muscle dysfunction associated with cachexia.
Authors
- Gahee Song (ORCID: https://orcid.org/0000-0002-3754-8294)
- Woo Yong Park (ORCID: https://orcid.org/0000-0003-4188-3826)
- Beomsu Kim (ORCID: https://orcid.org/0000-0002-2204-5571)
- Kwang Seok Ahn
- JIN‐HYUNG KIM
- Jae‐Young Um (ORCID: https://orcid.org/0000-0002-0568-9738)
- Ja Yeon Park (ORCID: https://orcid.org/0009-0003-2107-5087)
- Hyun Jeong Kwak
- Se Jin Jung
- Taekyoung Kong
- Jisoo Han
- Wenjun Jiao
- Sang Hee Kim
Institutions
- Kookmin University (KR)
- Kyung Hee University (KR)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1002/jcsm.70176
- Citations
- 1
- Primary Topic
- Pomegranate: compositions and health benefits
- Type
- article
- Field-Weighted Citation Impact
- 32.31
Funders
- National Research Foundation
- Wonkwang University
- Kyung Hee University
- Ministry of Science, ICT and Future Planning
- National Research Foundation of Korea