WO <sub>3</sub> -Based Heterogeneous Photocatalyzed Carboxamidation of Isocyanides for the Synthesis of Phenanthridine-6-carboxamides
An efficient photocatalytic protocol combining heterogeneous semiconductors as photocatalysts and Ph<sub>3</sub>N as a redox reagent was disclosed. Under this protocol, phenanthridine-6-carboxamides were formed in up to 93% yield via a multicomponent radical cascade annulation. Good substituent tolerance and gram-scale reaction showed the potential in fine chemical modification and pharmaceutical synthesis.
Authors
- Hongyu Shen (ORCID: https://orcid.org/0000-0003-1348-3497)
- Xiongjie Zhao
- Mengdi Wang (ORCID: https://orcid.org/0000-0002-2101-9507)
- Weimin He
- Linghui Lu
- Hong Chen
- Chao Wu
Institutions
- Hunan University of Science and Engineering (CN)
- Bioengineering Center (RU)
- University of South China (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1021/acs.joc.5c02146
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00