Exploring the impact of <scp>Cabotegravir‐Rilpivirine</scp> long‐acting on weight gain, body composition and quality of life in adults living with <scp>HIV</scp>

CAB + RPV LA was not associated with significant weight gain, clinically relevant changes in body composition or adverse metabolic effects over 48 weeks. Virologic suppression was maintained, renal laboratory parameters improved in prior INSTI users and treatment was well tolerated with increasing satisfaction. These findings support CAB + RPV LA as a safe, effective and metabolically neutral alternative to daily oral ART.

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Publication Details

Journal
HIV Medicine
Published
2026-01-28
DOI
https://doi.org/10.1111/hiv.70202
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
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article

Exploring the impact of Cabotegravir‐Rilpivirine long‐acting on weight gain, body composition and quality of life in adults living with HIV

Giulia Moi, A De Vito, S Uzzau, Antonella Cano et al.
HIV Medicine
HIV-related health complications and treatments
article

Exploring the impact of Cabotegravir‐Rilpivirine long‐acting on weight gain, body composition and quality of life in adults living with HIV

Giulia Moi, A De Vito, S Uzzau, Antonella Cano, Franca Deriu, Andrea Marongiu, Agnese Colpani, G Madeddu, Maria Grazia Catte, Maria Antonietta Deledda, Mariangela V Puci, A Spanu, Giovanni Sotgiu, Susanna Maria Nuvoli
article en

Abstract

CAB + RPV LA was not associated with significant weight gain, clinically relevant changes in body composition or adverse metabolic effects over 48 weeks. Virologic suppression was maintained, renal laboratory parameters improved in prior INSTI users and treatment was well tolerated with increasing satisfaction. These findings support CAB + RPV LA as a safe, effective and metabolically neutral alternative to daily oral ART.

HIV Medicine
University of Sassari (IT), Ospedale San Paolo (IT)
Openalex Percentile: Top 77%
HIV-related health complications and treatments
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Exploring the impact of <scp>Cabotegravir‐Rilpivirine</scp> long‐acting on weight gain, body composition and quality of life in adults living with <scp>HIV</scp> — Giulia Moi, A De Vito, et al. · HIV Medicine (2026) | TGRS Research Map | TGRS