Association between metabolic dysfunction-associated fatty liver disease and cardiovascular autonomic neuropathy in type 2 diabetes

MAFLD is independently associated with a higher prevalence of DCAN in patients with T2DM. The risk was further amplified when high FIB-4 index (FIB-4 >1.3) was present among those with MAFLD. Hence, screening for MAFLD and its associated high FIB-4 levels may help identify patients with T2DM at a higher risk of DCAN.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-28
DOI
https://doi.org/10.3389/fendo.2025.1711660
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Association between metabolic dysfunction-associated fatty liver disease and cardiovascular autonomic neuropathy in type 2 diabetes

Rong Peng, S. Zhang, Juan Liu, FU Xiaoying et al.
Frontiers in Endocrinology
Liver Disease Diagnosis and Treatment
article

Association between metabolic dysfunction-associated fatty liver disease and cardiovascular autonomic neuropathy in type 2 diabetes

Rong Peng, S. Zhang, Juan Liu, FU Xiaoying, Yaoyun Ao, Zeshan Huang, Enni Cen, Jian Kuang, Junnian Chen
article en

Abstract

MAFLD is independently associated with a higher prevalence of DCAN in patients with T2DM. The risk was further amplified when high FIB-4 index (FIB-4 >1.3) was present among those with MAFLD. Hence, screening for MAFLD and its associated high FIB-4 levels may help identify patients with T2DM at a higher risk of DCAN.

Frontiers in EndocrinologyVol. 16
Medical Center Hospital (US), Guangdong Academy of Medical Sciences (CN), Jiangmen Central Hospital (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 75%
Liver Disease Diagnosis and Treatment
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Association between metabolic dysfunction-associated fatty liver disease and cardiovascular autonomic neuropathy in type 2 diabetes — Rong Peng, S. Zhang, et al. · Frontiers in Endocrinology (2026) | TGRS Research Map | TGRS