Crocin and eugenol enhance radiosensitivity in oral squamous cell carcinoma cells via apoptotic pathways and cell cycle regulation. Type of study: in vitro
Crocin and eugenol effectively sensitize OSCC cells to IR by regulating apoptotic factors and promoting checkpoint arrest. Their favorable safety profiles and ability to enhance radiosensitivity support further in vivo studies and translational development as natural adjuncts in radiotherapy.
Authors
- Mohammad Taha Heidari
- Elham Keykha
- Mahdi Fasihi-Ramandi
- Samira Hajisadeghi
Institutions
- Baqiyatallah University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1186/s12906-026-05261-1
- Primary Topic
- Saffron Plant Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00