Real-world efficacy of enfortumab vedotin in Japanese patients with metastatic urothelial carcinoma stratified by EV-301 trial eligibility: a multicenter Bayesian restricted mean survival time analysis

EV exhibited real-world efficacy in Japanese mUC patients comparable to the eligible patients' outcomes in the EV-301 trial. Ineligible patients showed statistically inferior outcomes.

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Publication Details

Journal
Japanese Journal of Clinical Oncology
Published
2026-01-13
DOI
https://doi.org/10.1093/jjco/hyag012
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-world efficacy of enfortumab vedotin in Japanese patients with metastatic urothelial carcinoma stratified by EV-301 trial eligibility: a multicenter Bayesian restricted mean survival time analysis

Hiroko Sato, Kotaro Suzuki, Ichiro Yonese, Naoko Kawamura et al.
Japanese Journal of Clinical Oncology
Bladder and Urothelial Cancer Treatments
article

Real-world efficacy of enfortumab vedotin in Japanese patients with metastatic urothelial carcinoma stratified by EV-301 trial eligibility: a multicenter Bayesian restricted mean survival time analysis

Hiroko Sato, Kotaro Suzuki, Ichiro Yonese, Naoko Kawamura, Keita Izumi, Noboru Numao, Saori Araki, Takanobu Yamamoto, Sho Uehara, Atsushi Yoshinaga, Masahiro Toide, Masaharu Inoue, Hitoshi Masuda, Ryoji Takazawa, Hiroshi Fukushima, Yasuhisa Fujii, Hajime Tanaka, Shugo Yajima, Wei Chen, Yuki Nakamura, Akihiro Hirakawa, Soichiro Yoshida
article en

Abstract

EV exhibited real-world efficacy in Japanese mUC patients comparable to the eligible patients' outcomes in the EV-301 trial. Ineligible patients showed statistically inferior outcomes.

Japanese Journal of Clinical Oncology
Tokyo Medical and Dental University (JP), Tokyo Metropolitan Ohtsuka Hospital (JP), Tsuchiura Kyodo General Hospital (JP), Showa General Hospital (JP), JA Toride Medical Center (JP), Saitama Cancer Center (JP), The Cancer Institute Hospital (JP), Dokkyo Medical University Saitama Medical Center (JP), National Cancer Center Hospital East (JP), Kohnan Hospital (JP), Saitama Red Cross Hospital (JP), Tokyo Metropolitan Tama Medical Center (JP), Soka Municipal Hospital (JP), The University of Tokyo (JP)
Openalex Percentile: Top 75%
Bladder and Urothelial Cancer Treatments
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Real-world efficacy of enfortumab vedotin in Japanese patients with metastatic urothelial carcinoma stratified by EV-301 trial eligibility: a multicenter Bayesian restricted mean survival time analysis — Hiroko Sato, Kotaro Suzuki, et al. · Japanese Journal of Clinical Oncology (2026) | TGRS Research Map | TGRS