Trends and cross-country inequalities in the global burden of Alzheimer’s disease and other dementias among adults aged 65+ years, 1990–2021: a population based study with projections into 2050

The global number of people living with dementia nearly tripled from 1990 to 2021, mainly due to increases in population ageing and growth. The findings emphasize the need for comprehensive strategies to address ADOD, including prevention, early diagnosis, and effective management, with a focus on gender and regional disparities.

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Publication Details

Journal
Frontiers in Aging Neuroscience
Published
2026-01-29
DOI
https://doi.org/10.3389/fnagi.2025.1683158
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
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article

Trends and cross-country inequalities in the global burden of Alzheimer’s disease and other dementias among adults aged 65+ years, 1990–2021: a population based study with projections into 2050

Xiao Ma, Dean Gu, Mengxing Wang, Kai XU et al.
Frontiers in Aging Neuroscience
Dementia and Cognitive Impairment Research
article

Trends and cross-country inequalities in the global burden of Alzheimer’s disease and other dementias among adults aged 65+ years, 1990–2021: a population based study with projections into 2050

Xiao Ma, Dean Gu, Mengxing Wang, Kai XU, Long Wang, H Li, Sibo Liu, Guozhi Wu, Xiaoyan Lan, Jinjie Liu
article en

Abstract

The global number of people living with dementia nearly tripled from 1990 to 2021, mainly due to increases in population ageing and growth. The findings emphasize the need for comprehensive strategies to address ADOD, including prevention, early diagnosis, and effective management, with a focus on gender and regional disparities.

Frontiers in Aging NeuroscienceVol. 17
Qingdao University (CN), Capital Medical University (CN), Dalian Medical University (CN), Dalian University of Technology (CN), Beijing Tian Tan Hospital (CN), National Clinical Research Center for Digestive Diseases (CN), Second Affiliated Hospital of Dalian Medical University (CN), Dalian Municipal Central Hospital (CN), Affiliated Hospital of Qingdao University (CN), First Affiliated Hospital of Dalian Medical University (CN), University of Science and Technology Beijing (CN)
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Dementia and Cognitive Impairment Research
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Trends and cross-country inequalities in the global burden of Alzheimer’s disease and other dementias among adults aged 65+ years, 1990–2021: a population based study with projections into 2050 — Xiao Ma, Dean Gu, et al. · Frontiers in Aging Neuroscience (2026) | TGRS Research Map | TGRS