Associations of body mass index on worsening of heart failure and mortality in patients with heart failure and reduced left ventricular ejection fraction: a 10-year follow-up study (a NorthStar substudy)

In HFrEF patients, a BMI > 27 was not associated with increased mortality, contradicting the "obesity-survival paradox." In fact, patients with ischemic cardiomyopathy and a BMI > 27 may be associated with a higher mortality rate.

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Publication Details

Journal
Cardiovascular Diabetology
Published
2026-01-29
DOI
https://doi.org/10.1186/s12933-025-03062-3
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
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article

Associations of body mass index on worsening of heart failure and mortality in patients with heart failure and reduced left ventricular ejection fraction: a 10-year follow-up study (a NorthStar substudy)

Camilla Andersen, Lars Eriksen Videbæk, Mohamad El‐Chouli, Emil Loldrup Fosbøl et al.
Cardiovascular Diabetology
Cardiovascular Function and Risk Factors
article

Associations of body mass index on worsening of heart failure and mortality in patients with heart failure and reduced left ventricular ejection fraction: a 10-year follow-up study (a NorthStar substudy)

Camilla Andersen, Lars Eriksen Videbæk, Mohamad El‐Chouli, Emil Loldrup Fosbøl, Mariam Elmegaard, Caroline Garred, Lars Køber, Nina Nouhravesh, Daniel M. Christensen, Jawad H. Butt, Morten Schou, Morten Malmborg, Deewa Zahir
article en

Abstract

In HFrEF patients, a BMI > 27 was not associated with increased mortality, contradicting the "obesity-survival paradox." In fact, patients with ischemic cardiomyopathy and a BMI > 27 may be associated with a higher mortality rate.

Cardiovascular DiabetologyVol. 25(1)
University of Copenhagen (DK), Odense University Hospital (DK), Herlev Hospital (DK), Gentofte Hospital (DK), Rigshospitalet (DK)
Good health and well-being
Openalex Percentile: Top 76%
Cardiovascular Function and Risk Factors
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