Reconstruction of a Leaking Filtering Bleb after Trabeculectomy Using Amniotic Membrane Transplantation and Contralateral Conjunctival Autograft: A Case Report

Abstract Purpose: To describe the successful reconstruction of a leaking filtering bleb with necrotic conjunctiva long after trabeculectomy, using a double-layer amniotic membrane transplantation (AMT) combined with a contralateral conjunctival autograft. Methods: A 63-year-old woman developed a thin, avascular, leaking bleb ten years after trabeculectomy with mitomycin-C. After infection control with fortified antibiotics, reconstruction was performed using AMT over the scleral flap, a contralateral conjunctival–Tenon autograft, and an additional AM patch. Results: The ocular surface healed uneventfully. At two months, the bleb was sealed with good filtration and stable intraocular pressure. Best-corrected visual acuity improved to 0.2 logMAR. Conclusion: The combined use of amniotic membrane and contralateral conjunctival autograft offers an effective solution for late-onset bleb leaks when local conjunctiva is friable.

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Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-12-30
DOI
https://doi.org/10.5281/zenodo.18382477
Primary Topic
Glaucoma and retinal disorders
Type
article
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article

Reconstruction of a Leaking Filtering Bleb after Trabeculectomy Using Amniotic Membrane Transplantation and Contralateral Conjunctival Autograft: A Case Report

Pablo González, J IBANEZ ALPERTE, JM Duarte, Diana Pérez García et al.
Zenodo (CERN European Organization for Nuclear Research)
Glaucoma and retinal disorders
article

Reconstruction of a Leaking Filtering Bleb after Trabeculectomy Using Amniotic Membrane Transplantation and Contralateral Conjunctival Autograft: A Case Report

Pablo González, J IBANEZ ALPERTE, JM Duarte, Diana Pérez García, Francisco Javier Ascaso Puyuelo
article en

Abstract

Abstract Purpose: To describe the successful reconstruction of a leaking filtering bleb with necrotic conjunctiva long after trabeculectomy, using a double-layer amniotic membrane transplantation (AMT) combined with a contralateral conjunctival autograft. Methods: A 63-year-old woman developed a thin, avascular, leaking bleb ten years after trabeculectomy with mitomycin-C. After infection control with fortified antibiotics, reconstruction was performed using AMT over the scleral flap, a contralateral conjunctival–Tenon autograft, and an additional AM patch. Results: The ocular surface healed uneventfully. At two months, the bleb was sealed with good filtration and stable intraocular pressure. Best-corrected visual acuity improved to 0.2 logMAR. Conclusion: The combined use of amniotic membrane and contralateral conjunctival autograft offers an effective solution for late-onset bleb leaks when local conjunctiva is friable.

Zenodo (CERN European Organization for Nuclear Research)
Hospital Clínico Universitario Lozano Blesa (ES)
Openalex Percentile: Top 26%
Glaucoma and retinal disorders
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