Elevated thymidine kinase 1 expression at baseline predicts poor prognosis in breast cancer patients

Breast cancer patients presenting with high baseline TK1 expression are associated with significantly worse prognostic outcomes. Collectively, these findings support the clinical potential of TK1 assessment for prognostic risk stratification and treatment guidance, which merits further verification in large-scale, multicenter clinical trials.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-29
DOI
https://doi.org/10.3389/fonc.2026.1666576
Primary Topic
Advanced Breast Cancer Therapies
Type
article
Field-Weighted Citation Impact
0.00
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article

Elevated thymidine kinase 1 expression at baseline predicts poor prognosis in breast cancer patients

Y. Cheng, J. Zhao, Li Peng, Yuan Fang et al.
Frontiers in Oncology
Advanced Breast Cancer Therapies
article

Elevated thymidine kinase 1 expression at baseline predicts poor prognosis in breast cancer patients

Y. Cheng, J. Zhao, Li Peng, Yuan Fang, Tingting Zhao
article en

Abstract

Breast cancer patients presenting with high baseline TK1 expression are associated with significantly worse prognostic outcomes. Collectively, these findings support the clinical potential of TK1 assessment for prognostic risk stratification and treatment guidance, which merits further verification in large-scale, multicenter clinical trials.

Frontiers in OncologyVol. 16
Hebei Medical University (CN), Hebei North University (CN), First Affiliated Hospital of Hebei Medical University (CN)
Openalex Percentile: Top 76%
Advanced Breast Cancer Therapies
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