The therapeutic potential of ayahuasca in depression, generalized anxiety, and substance use disorders: modulation of the depressive burden in a longitudinal study

We concluded that the final variability in responses suggests that psychodynamic and clinical factors, such as the integration of the psychedelic experience and therapeutic support, play a crucial role in treatment effectiveness. This study contributes to the consolidation of psychedelic-assisted therapeutic protocols, highlighting the importance of continuous and personalized follow-up in the treatment of complex psychiatric conditions.