Detectability of hepatitis B virus DNA in peripheral blood mononuclear cells following long-term nucleos(t)ide analogue therapy-induced sustained viral suppression
HBV DNA may persist in PBMCs despite long-term nucleos(t)ide analogue therapy-induced sustained viral suppression. Pretreatment HBeAg positivity and elevated posttreatment qHBsAg can help identify patients at risk, highlighting the need to monitor extrahepatic reservoirs in CHB management.
Authors
- Elham Ahmed Hassan (ORCID: https://orcid.org/0000-0003-2575-758X)
- Mohamed A. El‐Mokhtar (ORCID: https://orcid.org/0000-0003-1943-8419)
- Mohamed A. Mekky (ORCID: https://orcid.org/0000-0003-1856-6988)
- Hani I Sayed (ORCID: https://orcid.org/0000-0001-7775-372X)
- Ahmad Farooq Alsayed Hasanain
- Mohammad Abdelhady Mohammad Omar
- Mohamed Zakaria Abu Rahma
Institutions
- Hospital for Tropical Diseases (VN)
- Assiut University (EG)
Publication Details
- Journal
- European Journal of Gastroenterology & Hepatology
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1097/meg.0000000000003136
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00