Bioenergetic and immunological characterization of cryopreserved peripheral blood mononuclear cells (PBMCs) isolated from blood and buffy coat
Cryopreservation of PBMCs has no effect on the measurement of bioenergetic parameters, although increased apoptotic cells are measured. Cryopreserved PBMCs show an increased immunological response, which must be taken into account when interpreting the results.
Authors
- Gunter Peter Eckert (ORCID: https://orcid.org/0000-0002-8002-9983)
- Fabian Dieter (ORCID: https://orcid.org/0009-0008-9901-5283)
- Alice Quentin (ORCID: https://orcid.org/0009-0009-5518-4330)
- Jendrik Grube
Institutions
- Justus-Liebig-Universität Gießen (DE)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2026-01-29
- DOI
- https://doi.org/10.3389/fmolb.2025.1716701
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Justus Liebig Universität Gießen
- Uniklinikum Giessen und Marburg