Benzimidazole and Benzimidazole Derivatives as Anticancer Scaffolds: A Review of Synthetic Approaches

The study highlights the chemical versatility of benzimidazole scaffolds and their structure-activity relationships in the design of anticancer drugs. Key findings emphasize efficient synthetic methodologies and functional modifications that enhance bioactivity. These insights contribute to the rational development of novel, potent anticancer agents, reinforcing the value of benzimidazoles in medicinal chemistry.