Sutureless-dehydrated amniotic membrane (Omnigen®) mounted on contact lens (OmniLenz®) in the treatment of small corneal perforations secondary to exposure keratitis in ICU patients

Omnigen®/OmniLenz® device provides a safe, effective, and non-invasive bedside treatment for small corneal perforations secondary to exposure keratitis in critically ill ICU patients. Its use enabled consistent tectonic restoration, rapid perforation closure, and resolution of infection-associated corneal pathology without procedure-related complications. This approach offers a practical alternative to urgent surgical intervention in patients unsuitable for operative care and may serve as a valuable addition to corneal perforation management protocols. Further studies with larger cohorts are needed to evaluate its safety and efficacy in larger perforations and to determine long-term outcomes, including corneal scarring and visual acuity.

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Publication Details

Journal
Medical Hypothesis Discovery & Innovation in Ophthalmology
Published
2025-12-17
DOI
https://doi.org/10.51329/mehdiophthal1532
Primary Topic
Corneal Surgery and Treatments
Type
article
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article

Sutureless-dehydrated amniotic membrane (Omnigen®) mounted on contact lens (OmniLenz®) in the treatment of small corneal perforations secondary to exposure keratitis in ICU patients

Hamad Alshatti, Rola Y. Khachaba, Mubarak Alrasheedi, Yousef Taleb Ali et al.
Medical Hypothesis Discovery & Innovation in Ophthalmology
Corneal Surgery and Treatments
article

Sutureless-dehydrated amniotic membrane (Omnigen®) mounted on contact lens (OmniLenz®) in the treatment of small corneal perforations secondary to exposure keratitis in ICU patients

Hamad Alshatti, Rola Y. Khachaba, Mubarak Alrasheedi, Yousef Taleb Ali, Nancy M. Lotfy
article en

Abstract

Omnigen®/OmniLenz® device provides a safe, effective, and non-invasive bedside treatment for small corneal perforations secondary to exposure keratitis in critically ill ICU patients. Its use enabled consistent tectonic restoration, rapid perforation closure, and resolution of infection-associated corneal pathology without procedure-related complications. This approach offers a practical alternative to urgent surgical intervention in patients unsuitable for operative care and may serve as a valuable addition to corneal perforation management protocols. Further studies with larger cohorts are needed to evaluate its safety and efficacy in larger perforations and to determine long-term outcomes, including corneal scarring and visual acuity.

Medical Hypothesis Discovery & Innovation in OphthalmologyVol. 14(4)
Cairo University (EG), Scarborough Health Network (CA), Farwaniya Hospital (KW), Department of Biological Sciences (BY)
Openalex Percentile: Top 28%
Corneal Surgery and Treatments
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Sutureless-dehydrated amniotic membrane (Omnigen®) mounted on contact lens (OmniLenz®) in the treatment of small corneal perforations secondary to exposure keratitis in ICU patients — Hamad Alshatti, Rola Y. Khachaba, et al. · Medical Hypothesis Discovery & Innovation in Ophthalmology (2025) | TGRS Research Map | TGRS