Cardiovascular and Cerebrovascular Events Linked to Abuse and Misuseof Sympathomimetic Nasal Decongestants: A Narrative Review of ClinicalEvidence
Sympathomimetic nasal decongestants are generally safe when used as directed. However, excessive or inappropriate use may lead to potentially fatal cerebrovascular and cardiovascular events. Healthcare professionals should thoroughly review patients' medication histories and provide clear instructions on proper use. Educating patients on the correct administration of sympathomimetic nasal decongestants and encouraging safer alternatives such as intranasal corticosteroids or saline sprays, when appropriate, is essential. Preventive measures, regulatory oversight, and interprofessional collaboration are crucial to ensuring safe use and reducing adverse outcomes.
Authors
- Naina Mohamed Pakkir Maideen (ORCID: https://orcid.org/0000-0002-6950-9783)
- Sulthan Al Rashid
Institutions
- Dubai Health Authority (AE)
- Mohammed Bin Rashid University of Medicine and Health Sciences (AE)
- Saveetha University (IN)
Publication Details
- Journal
- Cardiovascular & Hematological Agents in Medicinal Chemistry
- Published
- 2026-01-21
- DOI
- https://doi.org/10.2174/0118715257418908251126101911
- Primary Topic
- Nasal Surgery and Airway Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00