Cardiovascular and Cerebrovascular Events Linked to Abuse and Misuseof Sympathomimetic Nasal Decongestants: A Narrative Review of ClinicalEvidence

Sympathomimetic nasal decongestants are generally safe when used as directed. However, excessive or inappropriate use may lead to potentially fatal cerebrovascular and cardiovascular events. Healthcare professionals should thoroughly review patients' medication histories and provide clear instructions on proper use. Educating patients on the correct administration of sympathomimetic nasal decongestants and encouraging safer alternatives such as intranasal corticosteroids or saline sprays, when appropriate, is essential. Preventive measures, regulatory oversight, and interprofessional collaboration are crucial to ensuring safe use and reducing adverse outcomes.

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Publication Details

Journal
Cardiovascular & Hematological Agents in Medicinal Chemistry
Published
2026-01-21
DOI
https://doi.org/10.2174/0118715257418908251126101911
Primary Topic
Nasal Surgery and Airway Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Cardiovascular and Cerebrovascular Events Linked to Abuse and Misuseof Sympathomimetic Nasal Decongestants: A Narrative Review of ClinicalEvidence

Naina Mohamed Pakkir Maideen, Sulthan Al Rashid
Cardiovascular & Hematological Agents in Medicinal Chemistry
Nasal Surgery and Airway Studies
article

Cardiovascular and Cerebrovascular Events Linked to Abuse and Misuseof Sympathomimetic Nasal Decongestants: A Narrative Review of ClinicalEvidence

Naina Mohamed Pakkir Maideen, Sulthan Al Rashid
article en

Abstract

Sympathomimetic nasal decongestants are generally safe when used as directed. However, excessive or inappropriate use may lead to potentially fatal cerebrovascular and cardiovascular events. Healthcare professionals should thoroughly review patients' medication histories and provide clear instructions on proper use. Educating patients on the correct administration of sympathomimetic nasal decongestants and encouraging safer alternatives such as intranasal corticosteroids or saline sprays, when appropriate, is essential. Preventive measures, regulatory oversight, and interprofessional collaboration are crucial to ensuring safe use and reducing adverse outcomes.

Cardiovascular & Hematological Agents in Medicinal ChemistryVol. 24
Dubai Health Authority (AE), Mohammed Bin Rashid University of Medicine and Health Sciences (AE), Saveetha University (IN)
Good health and well-being
Openalex Percentile: Top 76%
Nasal Surgery and Airway Studies
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Cardiovascular and Cerebrovascular Events Linked to Abuse and Misuseof Sympathomimetic Nasal Decongestants: A Narrative Review of ClinicalEvidence — Naina Mohamed Pakkir Maideen, Sulthan Al Rashid · Cardiovascular & Hematological Agents in Medicinal Chemistry (2026) | TGRS Research Map | TGRS