Meta-analysis for the associations of serum C-reactive protein with delirium risk

Elevated serum CRP levels are significantly but modestly associated with delirium risk in diverse clinical populations. Given the observational nature of the included studies and high heterogeneity, these findings support CRP as a correlate, rather than a causal mediator, of delirium-related inflammation.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-01-29
DOI
https://doi.org/10.3389/fneur.2026.1728476
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Meta-analysis for the associations of serum C-reactive protein with delirium risk

Zhao-Yin Fu, Shuai Chen, Xiaoli Tan, Qi-xian Liang et al.
Frontiers in Neurology
Intensive Care Unit Cognitive Disorders
article

Meta-analysis for the associations of serum C-reactive protein with delirium risk

Zhao-Yin Fu, Shuai Chen, Xiaoli Tan, Qi-xian Liang, Zhi-wei Huang, Ye-zhao Li
article en

Abstract

Elevated serum CRP levels are significantly but modestly associated with delirium risk in diverse clinical populations. Given the observational nature of the included studies and high heterogeneity, these findings support CRP as a correlate, rather than a causal mediator, of delirium-related inflammation.

Frontiers in NeurologyVol. 17
Guangxi Medical University (CN)
Industry, innovation and infrastructure
Openalex Percentile: Top 75%
Intensive Care Unit Cognitive Disorders
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Meta-analysis for the associations of serum C-reactive protein with delirium risk — Zhao-Yin Fu, Shuai Chen, et al. · Frontiers in Neurology (2026) | TGRS Research Map | TGRS