Disturbed regulation of immunothrombosis in cerebral ischemia associated with SARS-CoV-2 infection
This pilot data suggest that a disturbed regulation of NETs in patients with SARS-CoV-2 infection may play a role in SARS-CoV-2 associated cerebral ischemia. These results highlight the importance of further investigating the role of NETs in immunothrombosis in the context of viral infections, to better understand its potential as a target for therapeutic strategies.
Authors
- Johanna Ernst (ORCID: https://orcid.org/0000-0002-5657-4703)
- Silke Akhdar
- Christine S. Falk (ORCID: https://orcid.org/0000-0003-1376-7318)
- Rabea Imker
- Verena Kopfnagel (ORCID: https://orcid.org/0000-0002-2060-5643)
- C Römmele
- Karin Weißenborn (ORCID: https://orcid.org/0000-0002-1157-8938)
- Marita Meurer (ORCID: https://orcid.org/0000-0001-9409-4922)
- Ramona Schuppner (ORCID: https://orcid.org/0000-0003-1952-9433)
- Jana Keil
- Maria M. Gabriel (ORCID: https://orcid.org/0000-0002-6862-5168)
- Isabel Bröhl
- Richard Plem
- Nicole de Buhr
- Sabine Blaschke
- NAPKON Investigators
- Gerrit M. Grosse
- Thomas Illig
Institutions
- Goethe University Frankfurt (DE)
- Goethe-Institute United Kingdom (GB)
- University of Veterinary Medicine Hannover, Foundation (DE)
- University Hospital Augsburg (DE)
- University Hospital of Basel (CH)
- University Medical Center (US)
- Medizinische Hochschule Hannover (DE)
- University of Veterinary Medicine (HU)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-29
- DOI
- https://doi.org/10.3389/fimmu.2026.1662418
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00