Transmural Healing is Associated With Higher Biological Drug Concentrations than Mucosal Healing in Crohn Disease
TH is associated with higher biological drug concentrations than MH in CD. Clinical trials are needed to further investigate whether dose escalation in patients with MH is helpful to achieve TH and evaluate the cost-effectiveness of this treat-to-TH strategy.
Authors
- Xin-Mei Zhao
- Pei-chun Xu
- Fachao Zhi
- Welera Haissou Elodie
- Wenjuan Zhang (ORCID: https://orcid.org/0000-0003-2922-0640)
- Zemin Han (ORCID: https://orcid.org/0000-0002-0635-2352)
- Li-hua Yan
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Therapeutic Drug Monitoring
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1097/ftd.0000000000001443
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00