Monitoring of virological response and acquired HIV-1 drug resistance among patients initiating antiretroviral therapy in the centre region of Cameroon

viral load monitoring reveals poor ART response in rural settings, which prompts the need for improving access to ART. Among those with unsuppressed VL, the burden and patterns of HIVDR are similar in both settings, likely due to the wide use of NNRTI-based ART. Viral susceptibility to INSTIs supports a possible switch to dolutegravir-based ART for optimal response.

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Publication Details

Journal
Pan African Medical Journal
Published
2025-11-21
DOI
https://doi.org/10.11604/pamj.2025.52.122.46773
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
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article

Monitoring of virological response and acquired HIV-1 drug resistance among patients initiating antiretroviral therapy in the centre region of Cameroon

Patrick Valère Tsouh Fokou, Evariste Molimbou, Fokam Jm, Jerome Fru-Cho et al.
Pan African Medical Journal
HIV/AIDS drug development and treatment
article

Monitoring of virological response and acquired HIV-1 drug resistance among patients initiating antiretroviral therapy in the centre region of Cameroon

Patrick Valère Tsouh Fokou, Evariste Molimbou, Fokam Jm, Jerome Fru-Cho, Ezéchiel Ngoufack Jagni Semengue, Christopher Dächert, Josef Eberle, Oliver Bosnjak, Naomi-Karell Etame, Stefanie Van Cleaf, Patrick Achiangia Njukeng, Bello Djoda, Maximilian Muenchhoff, Bauer Wilhelm, Oliver Till Keppler, Rodrigue Kamga, Abel Wade, Alain Nantchouang Megaptche, Charles Fokounang
article en

Abstract

viral load monitoring reveals poor ART response in rural settings, which prompts the need for improving access to ART. Among those with unsuppressed VL, the burden and patterns of HIVDR are similar in both settings, likely due to the wide use of NNRTI-based ART. Viral susceptibility to INSTIs supports a possible switch to dolutegravir-based ART for optimal response.

Pan African Medical JournalVol. 52
Université de Yaoundé I (CM), University of Buea (CM), Zimmer Biomet (Netherlands) (NL), University of Bamenda (CM), Centre International De Reference Chantal Biya (CM), Ludwig-Maximilians-Universität München (DE), Leipzig University (DE)
Good health and well-being
Openalex Percentile: Top 28%
HIV/AIDS drug development and treatment
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Monitoring of virological response and acquired HIV-1 drug resistance among patients initiating antiretroviral therapy in the centre region of Cameroon — Patrick Valère Tsouh Fokou, Evariste Molimbou, et al. · Pan African Medical Journal (2025) | TGRS Research Map | TGRS