Generalized steatitis in a miniature horse filly with laminitis and a positive outcome at 18-month follow-up.

A 12-month-old miniature horse filly was presented because of laminitis, suspected lymphangitis, and pyrexia. Although the filly's initial physical examination and diagnostic tests suggested an infectious etiology, ultrasonographic findings were suspicious for generalized steatitis. This was confirmed <i>via</i> histopathology. The filly experienced full recovery with continued resolution of clinical signs at 18 mo after presentation. This case included aspects similar to those of previously reported clinical presentations, as well as long-term follow-up in a breed that is not overrepresented, providing additional documentation of an uncommon condition in a miniature horse in North America. Key clinical message: Generalized steatitis is an uncommon condition in equids in North America. This case provided an example to aid in recognition, diagnosis, and treatment associated with a favorable outcome.