Transverse Comparison of Clinical Characteristics and Prognostic Factors in HIV-Infected Patients with Cytomegalovirus Encephalitis in Guangdong, China

HIV/CME patients with an unfavorable prognosis showed more obvious signs and symptoms of central nervous system infection, lower CSF Cl levels, and higher CSF CMV-DNA compared to patients with a favorable prognosis. Recognizing these indicators early and administering timely antiviral therapy before the disease progresses to CME are of great value in improving the survival rate of patients. Our findings extend beyond existing international studies by providing novel prognostic evidence in a Chinese cohort and offering a practical predictive tool for clinical risk stratification.

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Publication Details

Journal
Current HIV Research
Published
2026-01-22
DOI
https://doi.org/10.2174/011570162x397729251115050310
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
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article

Transverse Comparison of Clinical Characteristics and Prognostic Factors in HIV-Infected Patients with Cytomegalovirus Encephalitis in Guangdong, China

Mingyue Ren, Heping Zhao, Linghua Li, Jialong Guan et al.
Current HIV Research
Cytomegalovirus and herpesvirus research
article

Transverse Comparison of Clinical Characteristics and Prognostic Factors in HIV-Infected Patients with Cytomegalovirus Encephalitis in Guangdong, China

Mingyue Ren, Heping Zhao, Linghua Li, Jialong Guan, Weiying Lin, Yuping Ning, Yueping Li, Yu Meng
article en

Abstract

HIV/CME patients with an unfavorable prognosis showed more obvious signs and symptoms of central nervous system infection, lower CSF Cl levels, and higher CSF CMV-DNA compared to patients with a favorable prognosis. Recognizing these indicators early and administering timely antiviral therapy before the disease progresses to CME are of great value in improving the survival rate of patients. Our findings extend beyond existing international studies by providing novel prognostic evidence in a Chinese cohort and offering a practical predictive tool for clinical risk stratification.

Current HIV ResearchVol. 24
Guangzhou Eighth People's Hospital (CN), Guangzhou Medical University (CN)
Openalex Percentile: Top 76%
Cytomegalovirus and herpesvirus research
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