Miliary Tuberculosis With Immune Thrombocytopenia in 50‐Year‐Old Ethiopian Woman: A Case Report and Brief Review of Literature
Immune thrombocytopenia (ITP) is a rare but recognized hematologic complication of tuberculosis (TB), particularly miliary TB. We present a case of a 50-year-old female with severe thrombocytopenia and hemorrhagic manifestations secondary to miliary TB. The patient presented with mucocutaneous bleeding, anemia, and constitutional symptoms. Investigations revealed severe thrombocytopenia (11,000/μL), erythroid hyperplasia on bone marrow aspiration, and radiographic findings consistent with miliary TB, later confirmed by sputum GeneXpert. Management included short-course high-dose dexamethasone for acute bleeding, followed by anti-tuberculosis therapy (ATT), which led to sustained platelet recovery without further immunosuppression. This case highlights miliary TB as a reversible cause of secondary ITP and underscores the importance of investigating underlying infections in patients presenting with thrombocytopenia in TB-endemic regions.
Authors
- Hayatu Awel Abdela
- Tamirat Godebo Woyimo
- Sisay Tagese Tafese
- Ragasa Getachew Bayisa
Institutions
- Jimma University (ET)
- Wolkite University (ET)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1002/ccr3.71922
- Primary Topic
- Hematological disorders and diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00