A Rare Clown Nose Manifestation of Metastatic Eccrine Porocarcinoma: Case Study and Review of the Literature
The "clown nose" is a rare clinical presentation characterized by reddish-brown nodular lesions localized to the nasal tip. This distinctive sign has been associated with metastatic malignancies, genetic syndromes, and primary dermatologic conditions. We describe a rare case of metastatic eccrine porocarcinoma manifesting as a clown nose in a 54-year-old man with a history of metastatic lung squamous cell carcinoma. In addition, we performed a systematic literature review through PubMed to evaluate infiltration of the nose as a potential indicator of underlying tumor metastasis.
Authors
- Sheng Fang
- Qin-Xiao Wang
- Chao-Ke Zhang
- Feng-Zeng Li
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- American Journal of Dermatopathology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1097/dad.0000000000003152
- Primary Topic
- Cancer and Skin Lesions
- Type
- article
- Field-Weighted Citation Impact
- 0.00