Design and Efficacy of an Ultrashort Antimicrobial Peptide-levofloxacinConjugate Against Resistant Bacteria: A Novel Approach to CombatAntimicrobial Resistance

UP5-C-Levo is a promising therapeutic candidate for the treatment of MDR and biofilm-associated infections. Its strong antibacterial and antibiofilm activity, combined with a favorable safety profile, supports further preclinical development and potential clinical translation.

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Publication Details

Journal
Current Pharmaceutical Biotechnology
Published
2026-01-21
DOI
https://doi.org/10.2174/0113892010392077251119101656
Primary Topic
Antimicrobial Peptides and Activities
Type
article
Field-Weighted Citation Impact
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article

Design and Efficacy of an Ultrashort Antimicrobial Peptide-levofloxacinConjugate Against Resistant Bacteria: A Novel Approach to CombatAntimicrobial Resistance

Nizar Mhaidat, Ammar Almaaytah, Salsabeel H. Sabi, Aseel Rashdan
Current Pharmaceutical Biotechnology
Antimicrobial Peptides and Activities
article

Design and Efficacy of an Ultrashort Antimicrobial Peptide-levofloxacinConjugate Against Resistant Bacteria: A Novel Approach to CombatAntimicrobial Resistance

Nizar Mhaidat, Ammar Almaaytah, Salsabeel H. Sabi, Aseel Rashdan
article en

Abstract

UP5-C-Levo is a promising therapeutic candidate for the treatment of MDR and biofilm-associated infections. Its strong antibacterial and antibiofilm activity, combined with a favorable safety profile, supports further preclinical development and potential clinical translation.

Current Pharmaceutical BiotechnologyVol. 27
University of Jordan (JO), Jordan University of Science and Technology (JO), Hashemite University (JO)
Openalex Percentile: Top 75%
Antimicrobial Peptides and Activities
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