Evaluation of the Combined Therapeutic Potential of Turmeric and Donepezil on the Cholinergic System in a Mouse Model of AD-like Pathology

Turmeric monotherapy improved cognitive performance similarly to donepezil monotherapy in scopolamine-induced amnesic mice. These preliminary findings require further research, including dose optimization and clinical trials, to establish their clinical relevance.

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Publication Details

Journal
Current Drug Targets
Published
2026-01-19
DOI
https://doi.org/10.2174/0113894501433829251216060839
Primary Topic
Curcumin's Biomedical Applications
Type
article
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article

Evaluation of the Combined Therapeutic Potential of Turmeric and Donepezil on the Cholinergic System in a Mouse Model of AD-like Pathology

Syeda Ayesha Ali, Aliya Khalid, Saira Justin, Saadia Zahid et al.
Current Drug Targets
Curcumin's Biomedical Applications
article

Evaluation of the Combined Therapeutic Potential of Turmeric and Donepezil on the Cholinergic System in a Mouse Model of AD-like Pathology

Syeda Ayesha Ali, Aliya Khalid, Saira Justin, Saadia Zahid, Sumra Wajid Abbasi, Syeda Mehpara Farhat, Rabia Shakeel, Touqeer Ahmed, Aamra Mahboob, Maryam Masood, Sameera Zafar
article en

Abstract

Turmeric monotherapy improved cognitive performance similarly to donepezil monotherapy in scopolamine-induced amnesic mice. These preliminary findings require further research, including dose optimization and clinical trials, to establish their clinical relevance.

Current Drug TargetsVol. 27
National University of Medical Sciences (PK), National University of Sciences and Technology (PK)
Good health and well-being
Openalex Percentile: Top 74%
Curcumin's Biomedical Applications
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