Identification of RAGE Inhibitors from Curcuma caesia Roxb: Implications in Treatment against Diabetic Complications

These natural compounds exhibited promising drug-like characteristics against the target protein RAGE and may serve as lead compounds for the development of RAGE inhibitors. The study recommends further in vitro and in vivo investigations to assess the therapeutic potential of these identified compounds in the treatment of diabetic nephropathy.

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Publication Details

Journal
Current Diabetes Reviews
Published
2026-01-20
DOI
https://doi.org/10.2174/0115733998416568251122070701
Primary Topic
Advanced Glycation End Products research
Type
article
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article

Identification of RAGE Inhibitors from Curcuma caesia Roxb: Implications in Treatment against Diabetic Complications

Priyakshi Nath, Rupshikha Nath, Anupam Das Talukdar, Jagajjit Sahu et al.
Current Diabetes Reviews
Advanced Glycation End Products research
article

Identification of RAGE Inhibitors from Curcuma caesia Roxb: Implications in Treatment against Diabetic Complications

Priyakshi Nath, Rupshikha Nath, Anupam Das Talukdar, Jagajjit Sahu, Deepa Nath, Anil K. Pasupulati, Sibashish Kityania, Rajat Nath, Mriganka Das
article en

Abstract

These natural compounds exhibited promising drug-like characteristics against the target protein RAGE and may serve as lead compounds for the development of RAGE inhibitors. The study recommends further in vitro and in vivo investigations to assess the therapeutic potential of these identified compounds in the treatment of diabetic nephropathy.

Current Diabetes ReviewsVol. 22
Silchar Medical College and Hospital (IN), University of Hyderabad (IN), Department of Health & Family Welfare (IN), Assam University (IN), Tripura University (IN)
Good health and well-being
Openalex Percentile: Top 72%
Advanced Glycation End Products research
DOISourceOpenAlex
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