An Optimization Scheme Based on the Simulated Annealing Algorithm for In situ DNA Microarray Synthesis
The simulated annealing-based optimization strategy demonstrates clear advantages in improving DNA microarray synthesis efficiency while reducing material usage and waste, thereby enhancing cost-effectiveness. Such improvements offer practical benefits for applications, including gene editing, drug development, and DNA data storage.
Authors
- Kun Bi
- Hanlin Cheng
- Xiangwei Zhao
- Chu Cheng
- Xiucui Guan
- Qizhen Zhu
- Hengyu Li
- Pengfeng Xiao
Institutions
- Wuhan Polytechnic University (CN)
- State Key Laboratory of Digital Medical Engineering (CN)
- Southeast University (CN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2026-01-21
- DOI
- https://doi.org/10.2174/0113862073402626251112103715
- Primary Topic
- Gene expression and cancer classification
- Type
- article
- Field-Weighted Citation Impact
- 0.00