Mitochondrial and Antioxidant Activity as the Basis of the NeuroprotectiveEffect of Potential Multitarget Drugs for the Treatment of NeurodegenerativeDiseases
The combination of several pharmacophores in one molecule may not only result in the mere addition of the useful properties of each component, but may also give rise to new types of biological activity. The examples of the appearance of new properties in such multipharmacophore compounds, not inherent in the reference agents, discussed in our review, may be considered a prospective approach for creating a novel generation of neuroprotective agents.
Authors
- Alla Vadimovna Stavrovskaya
- Elena Feofanovna Shevtsova
- Sergey Olegovich Bachurin
- Vladimir Petrovich Fisenko
- Alexey Yuryevich Aksinenko
Institutions
- Sechenov University (RU)
- The Ministry of Education and Science of the Russian Federation (RU)
- Ministry of Internal Affairs of the Russian Federation (RU)
- Institute of Physiologically Active Compounds (RU)
Publication Details
- Journal
- Current Neuropharmacology
- Published
- 2026-01-19
- DOI
- https://doi.org/10.2174/011570159x409525251027064739
- Primary Topic
- Pharmacological Receptor Mechanisms and Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00