Mitochondrial and Antioxidant Activity as the Basis of the NeuroprotectiveEffect of Potential Multitarget Drugs for the Treatment of NeurodegenerativeDiseases

The combination of several pharmacophores in one molecule may not only result in the mere addition of the useful properties of each component, but may also give rise to new types of biological activity. The examples of the appearance of new properties in such multipharmacophore compounds, not inherent in the reference agents, discussed in our review, may be considered a prospective approach for creating a novel generation of neuroprotective agents.

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Publication Details

Journal
Current Neuropharmacology
Published
2026-01-19
DOI
https://doi.org/10.2174/011570159x409525251027064739
Primary Topic
Pharmacological Receptor Mechanisms and Effects
Type
article
Field-Weighted Citation Impact
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article

Mitochondrial and Antioxidant Activity as the Basis of the NeuroprotectiveEffect of Potential Multitarget Drugs for the Treatment of NeurodegenerativeDiseases

Alla Vadimovna Stavrovskaya, Elena Feofanovna Shevtsova, Sergey Olegovich Bachurin, Vladimir Petrovich Fisenko et al.
Current Neuropharmacology
Pharmacological Receptor Mechanisms and Effects
article

Mitochondrial and Antioxidant Activity as the Basis of the NeuroprotectiveEffect of Potential Multitarget Drugs for the Treatment of NeurodegenerativeDiseases

Alla Vadimovna Stavrovskaya, Elena Feofanovna Shevtsova, Sergey Olegovich Bachurin, Vladimir Petrovich Fisenko, Alexey Yuryevich Aksinenko
article en

Abstract

The combination of several pharmacophores in one molecule may not only result in the mere addition of the useful properties of each component, but may also give rise to new types of biological activity. The examples of the appearance of new properties in such multipharmacophore compounds, not inherent in the reference agents, discussed in our review, may be considered a prospective approach for creating a novel generation of neuroprotective agents.

Current NeuropharmacologyVol. 24
Sechenov University (RU), The Ministry of Education and Science of the Russian Federation (RU), Ministry of Internal Affairs of the Russian Federation (RU), Institute of Physiologically Active Compounds (RU)
Openalex Percentile: Top 77%
Pharmacological Receptor Mechanisms and Effects
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