Nasal Biomarkers of Acute Illness Severity and Predictors of Recurrent Wheeze in Infants Infected With Respiratory Syncytial Virus

We prospectively followed infants with primary RSV infection and identified associations between nasal gene expression, microbiome composition/function and acute disease severity and recurrent wheeze. Host transcriptional profiles during infection were predictive of recurrent wheeze within the following year.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2026-01-22
DOI
https://doi.org/10.1093/infdis/jiag049
Citations
1
Primary Topic
Respiratory viral infections research
Type
article
Field-Weighted Citation Impact
31.52
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article

Nasal Biomarkers of Acute Illness Severity and Predictors of Recurrent Wheeze in Infants Infected With Respiratory Syncytial Virus

ChinYi Chu, Xing Qiu, Mary T Caserta, Edward E Walsh et al.
1 citations
The Journal of Infectious Diseases
Respiratory viral infections research
31.52
article

Nasal Biomarkers of Acute Illness Severity and Predictors of Recurrent Wheeze in Infants Infected With Respiratory Syncytial Virus

ChinYi Chu, Xing Qiu, Mary T Caserta, Edward E Walsh, Steven R Gill, Anthony Corbett, Thomas J Mariani, Don Harrington, Ann L Gill
article en
1 citations

Abstract

We prospectively followed infants with primary RSV infection and identified associations between nasal gene expression, microbiome composition/function and acute disease severity and recurrent wheeze. Host transcriptional profiles during infection were predictive of recurrent wheeze within the following year.

The Journal of Infectious Diseases
University of Rochester Medical Center (US), Southern California Clinical and Translational Science Institute (US), Czech Academy of Sciences, Institute of Microbiology (CZ), Bipar (FR), University Of Medicine 1 Yangon (MM)
Good health and well-being
Openalex Percentile: Top 1%
Respiratory viral infections research
31.52
DOISourceOpenAlex
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