Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury
Valproate has pharmacological properties that point to its potential repositioning as an adjuvant in improving several outcomes in AKI and potentially avoiding progression to chronic kidney disease.
Authors
- Isadora G. Almeida
- João P. M. Veloso‐Santos
- Jarlene A. Lopes
- Humberto Muzi‐Filho
- Adalberto Vieyra
- Danilo Alves‐Bezerra
- Luiza B. Negreiros
- Glória Costa‐Sarmento
- Amaury Pereira‐Acácio
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Instituto Federal do Rio de Janeiro (BR)
- Universidade Unigranrio (BR)
- Czech Academy of Sciences, Institute of Biophysics (CZ)
- National Institute of Science and Technology for Structural Biology and Bioimaging (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- British Journal of Clinical Pharmacology
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1002/bcp.70456
- Primary Topic
- Histone Deacetylase Inhibitors Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Universidade Federal do Rio de Janeiro
- Division of Graduate Education