Distinct Effects of Autologous Hematopoietic Stem Cell Transplantation on T Cell Composition and Profile in Refractory Crohn’s Disease

Autologous hematopoietic stem cell transplantation had pronounced effects on the peripheral T cell composition, especially in responders. Changes in T cell subset composition were more pronounced than changes in the functional T cell profile.

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Publication Details

Journal
Inflammatory Bowel Diseases
Published
2025-12-25
DOI
https://doi.org/10.1093/ibd/izaf331
Primary Topic
Inflammatory Bowel Disease
Type
article
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article

Distinct Effects of Autologous Hematopoietic Stem Cell Transplantation on T Cell Composition and Profile in Refractory Crohn’s Disease

Herma H Fidder, Eveline M Delemarre, Bas Oldenburg, David P Hoytema van Konijnenburg et al.
Inflammatory Bowel Diseases
Inflammatory Bowel Disease
article

Distinct Effects of Autologous Hematopoietic Stem Cell Transplantation on T Cell Composition and Profile in Refractory Crohn’s Disease

Herma H Fidder, Eveline M Delemarre, Bas Oldenburg, David P Hoytema van Konijnenburg, Femke van Wijk, M Marlot van der Wal, Elise S Saager, Theo van den Broek, Lisanne Lutter, Nofel Mahmmod
article en

Abstract

Autologous hematopoietic stem cell transplantation had pronounced effects on the peripheral T cell composition, especially in responders. Changes in T cell subset composition were more pronounced than changes in the functional T cell profile.

Inflammatory Bowel DiseasesVol. 32(3)
Boston Children's Hospital (US), University Medical Center Utrecht (NL), St. Antonius Ziekenhuis (NL), Amsterdam Neuroscience (NL), Amsterdam University Medical Centers (NL), University of Amsterdam (NL)
Good health and well-being
Openalex Percentile: Top 22%
Inflammatory Bowel Disease
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Distinct Effects of Autologous Hematopoietic Stem Cell Transplantation on T Cell Composition and Profile in Refractory Crohn’s Disease — Herma H Fidder, Eveline M Delemarre, et al. · Inflammatory Bowel Diseases (2025) | TGRS Research Map | TGRS