Unveiling the molecular mechanisms of burn injury through integrated single-cell and bulk transcriptomic analysis
This study provides novel insights into the immunological microenvironment of burn injuries. Despite limitations including a modest sample size and lack of experimental validation, our findings establish a foundation for future investigations into targeted immunotherapeutic strategies, potentially improving clinical outcomes and advancing personalized treatment approaches for burn patients.
Authors
- Yanyan Pan
- Xiaoyu Zhu
- Youfen Fan
- Jiliang Li
- Shengyong Cui
- Neng Huang
- Xin Le
Institutions
- Ningbo University (CN)
- Ningbo No. 2 Hospital (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-01-27
- DOI
- https://doi.org/10.1371/journal.pone.0341725
- Primary Topic
- Burn Injury Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00