A robustness-inclusive comparison of proton- versus photon-based whole-pelvic radiotherapy for prostate cancer within a randomised clinical trial

Within this robustness-inclusive multicentre comparison study, proton-based WPRT maintained target coverage comparable to photon therapy and consistently reduced low- and intermediate-dose exposure to normal tissues, while demonstrating preserved robustness under the influence of inter-fractional variation.

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Publication Details

Journal
Radiotherapy and Oncology
Published
2026-01-27
DOI
https://doi.org/10.1016/j.radonc.2026.111404
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

A robustness-inclusive comparison of proton- versus photon-based whole-pelvic radiotherapy for prostate cancer within a randomised clinical trial

Bjarke Mortensen, Liliana Stolarczyk, Susan Blak Nyrup Biancardo, Christine Vestergård Madsen et al.
Radiotherapy and Oncology
Advanced Radiotherapy Techniques
article

A robustness-inclusive comparison of proton- versus photon-based whole-pelvic radiotherapy for prostate cancer within a randomised clinical trial

Bjarke Mortensen, Liliana Stolarczyk, Susan Blak Nyrup Biancardo, Christine Vestergård Madsen, Kirsten Legaard Jakobsen, Rasmus Havelund, Jimmi Søndergaard, Ludvig Paul Muren, Dorthe Yakymenko, Henriette Lindberg, Stine Elleberg Petersen, Anders Schwartz Vittrup, Sofie Tilbæk, Terje Andersen, Kasper Lind Laursen, Steffen Bjerre Hokland
article en

Abstract

Within this robustness-inclusive multicentre comparison study, proton-based WPRT maintained target coverage comparable to photon therapy and consistently reduced low- and intermediate-dose exposure to normal tissues, while demonstrating preserved robustness under the influence of inter-fractional variation.

Radiotherapy and OncologyVol. 217
Aarhus University (DK), Aalborg University Hospital (DK), Aarhus University Hospital (DK), Gentofte Hospital (DK), Zealand University Hospital (DK), Vejle Sygehus (DK), Danish Pain Research Center (DK)
Aarhus Universitet
Good health and well-being
Openalex Percentile: Top 77%
Advanced Radiotherapy Techniques
DOIOpen Access PDFOpenAlex
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A robustness-inclusive comparison of proton- versus photon-based whole-pelvic radiotherapy for prostate cancer within a randomised clinical trial — Bjarke Mortensen, Liliana Stolarczyk, et al. · Radiotherapy and Oncology (2026) | TGRS Research Map | TGRS