Role of cytokine levels in pathogen classification and prognosis of pediatric septic shock
Elevated IL-6 and IL-10 levels are valuable for predicting 28-day mortality and identifying gram-negative bacteremia in pediatric patients with septic shock. IFN-γ and TNF-α levels also have significant value for predicting 28-day mortality. Moreover, the IL-6 level was an independent risk factor for 28-day mortality.
Authors
- Ruichen Zhang
- Haixin Huang
- Yueqiang Fu
- Guangyan Du
- Chengjun Liu
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-27
- DOI
- https://doi.org/10.3389/fimmu.2026.1714948
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chongqing Medical University