APRI and FIB-4 indices as systemic fibrosis markers in proliferative vitreoretinopathy

The APRI and FIB-4 indices did not reveal a statistically significant difference in distinguishing the development of proliferative vitreoretinopathy. These findings support that the pathogenesis of PVR is primarily driven by inflammatory and fibroproliferative processes occurring within the local vitreoretinal microenvironment rather than by systemic fibrosis.

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Publication Details

Journal
BMC Ophthalmology
Published
2026-01-27
DOI
https://doi.org/10.1186/s12886-026-04640-z
Primary Topic
Retinal and Macular Surgery
Type
article
Field-Weighted Citation Impact
0.00
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article

APRI and FIB-4 indices as systemic fibrosis markers in proliferative vitreoretinopathy

Eda Zeynep Kılıç, Nurullah Koçak
BMC Ophthalmology
Retinal and Macular Surgery
article

APRI and FIB-4 indices as systemic fibrosis markers in proliferative vitreoretinopathy

Eda Zeynep Kılıç, Nurullah Koçak
article en

Abstract

The APRI and FIB-4 indices did not reveal a statistically significant difference in distinguishing the development of proliferative vitreoretinopathy. These findings support that the pathogenesis of PVR is primarily driven by inflammatory and fibroproliferative processes occurring within the local vitreoretinal microenvironment rather than by systemic fibrosis.

BMC OphthalmologyVol. 26(1)
Ondokuz Mayıs University (TR)
Zero hunger
Openalex Percentile: Top 78%
Retinal and Macular Surgery
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APRI and FIB-4 indices as systemic fibrosis markers in proliferative vitreoretinopathy — Eda Zeynep Kılıç, Nurullah Koçak · BMC Ophthalmology (2026) | TGRS Research Map | TGRS