A Quantitative Lung Mucin Score to Identify Chronic Bronchitis

The MUCQ metric was superior in distinguishing patients with CB compared to a total mucin concentration. Trials are needed to ascertain the prospective use of MUCQ metrics in research and clinical settings for assessment, management, and tracking therapeutic responses in CB and potentially other muco-obstructive conditions. (Funded by the National Institutes of Health and others.).

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Publication Details

Journal
NEJM Evidence
Published
2026-01-27
DOI
https://doi.org/10.1056/evidoa2500051
Citations
1
Primary Topic
Respiratory and Cough-Related Research
Type
article
Field-Weighted Citation Impact
36.44
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article

A Quantitative Lung Mucin Score to Identify Chronic Bronchitis

Christopher B. Cooper, Eugene R. Bleecker, Fernando J. Martinez, Stephanie A. Christenson et al.
1 citations
NEJM Evidence
Respiratory and Cough-Related Research
36.44
article

A Quantitative Lung Mucin Score to Identify Chronic Bronchitis

Christopher B. Cooper, Eugene R. Bleecker, Fernando J. Martinez, Stephanie A. Christenson, Richard E. Kanner, R. Graham Barr, Eric A. Hoffman, MeiLan K. Han, Prescott G. Woodruff, Giorgia Radicioni, Annette T. Hastie, Richard C. Boucher, Mehmet Kesimer, Neil E. Alexis, Robert Paine, Amina A. Ford, Nadia N. Hansel, Agathe Ceppe
article en
1 citations

Abstract

The MUCQ metric was superior in distinguishing patients with CB compared to a total mucin concentration. Trials are needed to ascertain the prospective use of MUCQ metrics in research and clinical settings for assessment, management, and tracking therapeutic responses in CB and potentially other muco-obstructive conditions. (Funded by the National Institutes of Health and others.).

NEJM EvidenceVol. 5(2)
University of North Carolina at Chapel Hill (US), UMass Memorial Health Care (US), University of Arizona (US), Johns Hopkins University (US), University of California, Los Angeles (US), University of Massachusetts Chan Medical School (US), University of Utah (US), Columbia University Irving Medical Center (US), Johns Hopkins Medicine (US), University of Iowa Hospitals and Clinics (US), Lung Institute (US), University of California San Francisco Medical Center (US), Michigan Medicine (US), Wake Forest University (US), Columbia University (US)
Good health and well-being
Openalex Percentile: Top 1%
Respiratory and Cough-Related Research
36.44
DOISourceOpenAlex
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A Quantitative Lung Mucin Score to Identify Chronic Bronchitis — Christopher B. Cooper, Eugene R. Bleecker, et al. · NEJM Evidence (2026) | TGRS Research Map | TGRS