Frailty, comorbidity and survival comparisons between populations eligible for screening according to risk factor versus risk score criteria: results from the Yorkshire Lung Screening Trial

These data suggest that currently used risk models identify populations with a small increase in moderate/severe frailty and multimorbidity compared to the USPSTF<sub>2021</sub> criteria, but there is no evidence to suggest that this results in differences in 3-year overall survival.

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Publication Details

Journal
Thorax
Published
2026-01-27
DOI
https://doi.org/10.1136/thorax-2024-222487
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Frailty, comorbidity and survival comparisons between populations eligible for screening according to risk factor versus risk score criteria: results from the Yorkshire Lung Screening Trial

Philip A Crosbie, Rebecca J Beeken, Samuel D Relton, Rhian Gabe et al.
Thorax
Lung Cancer Diagnosis and Treatment
article

Frailty, comorbidity and survival comparisons between populations eligible for screening according to risk factor versus risk score criteria: results from the Yorkshire Lung Screening Trial

Philip A Crosbie, Rebecca J Beeken, Samuel D Relton, Rhian Gabe, Richard D Neal, Neil Hancock, Matthew E J Callister, Daniel Vulkan, Martel Brown, Hui Zhen Tam, Andrew Clegg, Anas Almatrafi, Kate E Best
article en

Abstract

These data suggest that currently used risk models identify populations with a small increase in moderate/severe frailty and multimorbidity compared to the USPSTF<sub>2021</sub> criteria, but there is no evidence to suggest that this results in differences in 3-year overall survival.

Thorax
University of Leeds (GB), Queen Mary University of London (GB), Umm al-Qura University (SA), University of Exeter (GB), Leeds Teaching Hospitals NHS Trust (GB), Manchester Academic Health Science Centre (GB), University College London (GB)
National Institute for Health and Care Research, Umm Al-Qura University, Manchester Biomedical Research Centre
Openalex Percentile: Top 77%
Lung Cancer Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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Frailty, comorbidity and survival comparisons between populations eligible for screening according to risk factor versus risk score criteria: results from the Yorkshire Lung Screening Trial — Philip A Crosbie, Rebecca J Beeken, et al. · Thorax (2026) | TGRS Research Map | TGRS