Age-dependent clinical, molecular, and prognostic differences in patients with AML: a retrospective study

This study revealed that patients aged ≥50 years displayed more complex genetic aberration profiles and experienced significantly poorer prognoses compared to their younger counterparts. These findings provided novel insights for optimizing treatment strategies for middle-aged and elderly AML patients in the Chinese population.

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Publication Details

Journal
Hematology
Published
2026-01-27
DOI
https://doi.org/10.1080/16078454.2026.2622254
Primary Topic
Acute Myeloid Leukemia Research
Type
article
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article

Age-dependent clinical, molecular, and prognostic differences in patients with AML: a retrospective study

Hong Liu, Yue Chen, Yang Su, Zhi Li et al.
Hematology
Acute Myeloid Leukemia Research
article

Age-dependent clinical, molecular, and prognostic differences in patients with AML: a retrospective study

Hong Liu, Yue Chen, Yang Su, Zhi Li, Liang Yu, Jingjing Ma, Chunling Wang, Tingting Ji, Shandong Tao, Qiuni Chen, Yuye Shi
article en

Abstract

This study revealed that patients aged ≥50 years displayed more complex genetic aberration profiles and experienced significantly poorer prognoses compared to their younger counterparts. These findings provided novel insights for optimizing treatment strategies for middle-aged and elderly AML patients in the Chinese population.

HematologyVol. 31(1)
Xuzhou Medical College (CN), Second People’s Hospital of Huai’an (CN), Nanjing Medical University (CN)
No poverty
Openalex Percentile: Top 79%
Acute Myeloid Leukemia Research
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