Clinical Effects of Recently Developed Antipsychotic Drugs in Schizophrenia

Promising new antipsychotic drugs include cariprazine, brexpiprazole, lumateperone, ulotaront, and xanomeline combined with trospium. Phase 3 clinical studies have shown therapeutic effects superior to those achieved with second-generation antipsychotic drugs.

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Publication Details

Journal
Central Nervous System Agents in Medicinal Chemistry
Published
2026-01-21
DOI
https://doi.org/10.2174/0118715249384914251122074130
Primary Topic
Receptor Mechanisms and Signaling
Type
article
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0.00
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article

Clinical Effects of Recently Developed Antipsychotic Drugs in Schizophrenia

Rafael Coveñas, Felix-Martin Werner
Central Nervous System Agents in Medicinal Chemistry
Receptor Mechanisms and Signaling
article

Clinical Effects of Recently Developed Antipsychotic Drugs in Schizophrenia

Rafael Coveñas, Felix-Martin Werner
article en

Abstract

Promising new antipsychotic drugs include cariprazine, brexpiprazole, lumateperone, ulotaront, and xanomeline combined with trospium. Phase 3 clinical studies have shown therapeutic effects superior to those achieved with second-generation antipsychotic drugs.

Central Nervous System Agents in Medicinal ChemistryVol. 26
Universidad de Salamanca (ES), Instituto de Estudios de Ciencias de la Salud de Castilla y León (ES)
Good health and well-being
Openalex Percentile: Top 77%
Receptor Mechanisms and Signaling
DOISourceOpenAlex
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Clinical Effects of Recently Developed Antipsychotic Drugs in Schizophrenia — Rafael Coveñas, Felix-Martin Werner · Central Nervous System Agents in Medicinal Chemistry (2026) | TGRS Research Map | TGRS