Lazertinib with stereotactic body radiotherapy in oligometastatic EGFR-mutant non-small-cell lung cancer

In treatment-naive, EGFR-mutant oligometastatic NSCLC, adding upfront SBRT to lazertinib is a viable therapeutic option with a manageable safety profile.

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Publication Details

Journal
ESMO Open
Published
2026-01-27
DOI
https://doi.org/10.1016/j.esmoop.2025.106057
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Lazertinib with stereotactic body radiotherapy in oligometastatic EGFR-mutant non-small-cell lung cancer

M.H. Hong, S. Yoon, S.Y. Song, S. Jo et al.
ESMO Open
Lung Cancer Treatments and Mutations
article

Lazertinib with stereotactic body radiotherapy in oligometastatic EGFR-mutant non-small-cell lung cancer

M.H. Hong, S. Yoon, S.Y. Song, S. Jo, S.S. Lee, H.J. Kim, H.K. Ahn, S.J. Choi, K.H. Kim, J.B. Lee, H. Park, S.M. Lim, B.C. Cho, H.I. Yoon
article en

Abstract

In treatment-naive, EGFR-mutant oligometastatic NSCLC, adding upfront SBRT to lazertinib is a viable therapeutic option with a manageable safety profile.

ESMO OpenVol. 11(2)
Ulsan College (KR), Yonsei University (KR), Severance Hospital (KR), Asan Medical Center (KR), Samsung Medical Center (KR), University of Ulsan (KR), Gachon University Gil Medical Center (KR), Inje University Haeundae Paik Hospital (KR), Yonsei University Health System (KR)
Good health and well-being
Openalex Percentile: Top 78%
Lung Cancer Treatments and Mutations
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Lazertinib with stereotactic body radiotherapy in oligometastatic EGFR-mutant non-small-cell lung cancer — M.H. Hong, S. Yoon, et al. · ESMO Open (2026) | TGRS Research Map | TGRS